I am on thyroid hormone and cannot lose weight no matter what I do.

I am hypothyroid (on Synthroid) and cannot lose weight no matter what I do. I am not a big eater and chose many low-fat items as part of the diet. I exercise 45 minutes per day (brisk walking). Is it possible that there could be another reason for the inability to lose weight? Have you heard of something called hypothalamus? I read a magazine article that says if this is out of whack, then no diet will ever work. Do you know how to correct this situation if you are familiar with it? The article was about acupuncture and herbs. What are your thoughts on this?

Your hypothalamus measures the temperature and solids in your blood. When your body temperature, glucose or salt in your blood goes too high, your hypothalamus signals you to drink fluids. The more recent research has focused on the hypothalamus as the organ that signals eating and satiety (feeling of fullness). Research on eating disorders (anorexia and bulimia) have focused on this gland and the secretion of several neurotransmitters (epinephrine, norepinephrine, and serotonin as influencing eating behaviors.

I do not know about the influence acupuncture or herbs would have on the weight loss though I have read many promising articles on the use of both in medicine.

I would suggest you ask your doctor to measure your blood to determine if you are taking enough synthetic thyroxin to be therapeutically effective for your metabolism. Many systems in your body are interrelated and dependent on many hormones and biochemicals to function normally. I would also suggest you ask to see a dietitian who can evaluate your diet and energy needs to make recommendations for weight loss.